Familial Glaucoma.
نویسندگان
چکیده
FAMILIAL primary glaucoma is a recognized entity. It has been reported in the literature quite regularly, though not frequently. Benedict (1842) was the first to recognize the familial inheritance of glaucoma, and other authors followed with large collections of such cases. Something like 18 per cent. of the total cases of glaucoma show an hereditary component (Havener, 1955). Duke-Elder (1940) stated that the inheritance was dominant and could be transmitted by each sex, the transmitting parent being usually affected. The trait being dominant, the succeeding generation shows anticipation (von Graefe, 1869). The onset of familial glaucoma occurs some 20 years earlier than other primary cases of glaucoma, and the offspring develops glaucoma some 10 years earlier than the parent. Recently we came across a family of a father and his three sons all suffering from primary glaucoma, which typifies the above statement in many details.
منابع مشابه
Evaluation of various factors relating to intraocular pressure and C/D ratio
Introduction: Intraocular pressure (IOP) is determined by three factors: the rate of aqueous humor production by the ciliary’s body, the resistances to aqueous out flow across the trabecular meshwork and the level of episcleral vessel pressure. IOP varies with a number of factors, including: age, sex, race, systemic disease and diurnal variation. The purpose of this study is measurement of IO...
متن کاملDisease severity of familial glaucoma compared with sporadic glaucoma.
OBJECTIVE To determine whether there is a difference in disease severity between familial and sporadic primary open-angle glaucoma (POAG). METHODS A cross-sectional study design compared the distribution of Glaucoma Inheritance Study in Tasmania (GIST) severity scores of patients with genealogically confirmed familial POAG and those with sporadic POAG. The GIST severity scores provide a combi...
متن کاملFamilial aggregation of primary open angle glaucoma in Shanghai, China
PURPOSE To identify familial aggregation of primary open angle glaucoma (POAG) in first-degree relatives in Shanghai, China. METHODS This was a prospective case-control study. First-degree relatives of 113 POAG patients and 119 normal controls underwent a standardized ophthalmic examination. Each participant was diagnosed as normal, glaucoma suspect or glaucoma. The prevalence of glaucoma and...
متن کاملManagement of glaucoma in a case of familial aniridia by trabeculectomy.
Aniridia is a rare developmental disorder. Glaucoma and complications associated with glaucoma surgery are a major cause of blindness in patients with aniridia. We describe here a case of a nine year old boy who presented with familial aniridia of both eyes along with glaucoma. He was treated by trabeculectomy of both eyes, which was successful in controlling the glaucoma.
متن کاملSurvey of familial glaucoma shows a high incidence of cytochrome P450, family 1, subfamily B, polypeptide 1 (CYP1B1) mutations in non-consanguineous congenital forms in a Spanish population
PURPOSE To identify myocilin (MYOC) and cytochrome P450, family 1, subfamily B, polypeptide 1 (CYP1B1) mutations in a Spanish population with different clinical forms of familial glaucoma or ocular hypertension (OHT). METHODS Index patients from 226 families participated in this study. Patients were diagnosed with familial glaucoma or OHT by complete ophthalmologic examination. Screening for ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- The British journal of ophthalmology
دوره 45 11 شماره
صفحات -
تاریخ انتشار 1961